Ryanair flies daily in summer months from Stansted to Pescara ,
3 times a week other times of year-50 min drive
Other daily flights to Rome,Ciampino from local British airports -Dublin, East Midlands, Durham, Luton, Stansted, Glasgow, and Liverpool -approx.2.5 hrs drive from Rome.
Ancona is another airport within easy driving distance -approx.2hrs

EasyJet to Rome from Aberdeen, Belfast, Bournmouth, Bristol, Cork, Doncaster, Edinburgh, Glasgow, Inverness, Liverpool, Newcastle, Nottingham and Shannon

Cars can be hired from Pescara and Rome airports with easy access from the airports to main road networks. We always use Herz but other companies include Auto Europa, Avis or Europecar.