50 Best Vacation Rentals in Los Santos Province - Holiday Lettings - Cabins

Close

View larger map

Also consider

Pedasi
48 properties
Las Tablas
6 properties

Los Santos Province

No dates Enter dates for accurate prices -

Adults, Children

Enter dates for more accurate prices

Payment Protection
To book this vacation rental you need to pay through the Holiday Lettings website. We can’t protect your payment if you don’t pay through us. Learn more

58 Vacation rentals

30

Vacation home in Los Santos Province

Pedasi / Playa Venao

3 6 Min stay varies

  • 3 bedrooms
  • Sleeps 6
  • Min stay varies
  • Swimming pool
  • Child friendly
  • Air conditioning
This stunning 3 bedroom home with pool is set up on a cliff overlooking the Pacific Ocean. There is direct access to the very secluded beach below with a custom wood walkway. The infinity edge pool allows you to have unlimited views while going for a swim. There is a …see more

from $300 / night

$1,700 / week

Book View

Responds fast!
avg. 3 hours 48 minutes

from $300 / night

19

Home rental in Pedasi

Los Santos Province / Pedasi

2 4 Min stay varies

  • 2 bedrooms
  • Sleeps 4
  • Min stay varies
  • Child friendly
  • Air conditioning
  • Private garden
This home was just recently built and hardly even lived in! Comes with brand new appliances, nice wood touches throughout, and high ceilings. The space can accommodate 4 adults comfortably with 2 bedrooms and 2 1/2 baths. The living room has high quality furniture wi …see more

from $100 / night

$600 / week

Book View

Responds fast!
avg. 3 hours 48 minutes

from $100 / night

(3) Very Good 

15

Home rental in Los Santos Province with shared pool

Los Santos Province / Pedasi

4 8 1 night min

  • 4 bedrooms
  • Sleeps 8
  • 1 night min
  • Swimming pool
  • Child friendly
  • Air conditioning
This beautiful secluded home has been designed by famous architect Gilles Saint-Gilles. Villa Jungla enjoys beautiful ocean views over the Pacific; it features a large terrace where you will feel the ocean breezes and a gorgeous pool. Set in lush gardens surrounded by …see more

from $275 / night

$1,925 / week

Book View

from $275 / night

15

Pedasi Vacation home rental

Los Santos Province / Pedasi

2 4 Min stay varies

  • 2 bedrooms
  • Sleeps 4
  • Min stay varies
  • Child friendly
  • Air conditioning
  • Private garden
Comfortable 2 bedroom 2 bath home in the town of Pedasi surrounded by trees. Walking distance to town where you can enjoy all the restaurants and shopping. Bike or drive to the several beaches that are close by. Our village is a farming and fishing village, where you …see more

from $75 / night

$400 / week

Book View

Responds fast!
avg. 3 hours 48 minutes

from $75 / night

22

Pedasi Vacation home rental

Los Santos Province / Pedasi

3 6 Min stay varies

  • 3 bedrooms
  • Sleeps 6
  • Min stay varies
  • Child friendly
  • Air conditioning
  • Private garden
This is a beautiful, 3 bedroom 1 bath home in the small town of Pocri. There is a huge wrap around covered porch for you to enjoy the quiet town. The house is completely fenced with grass and beautiful trees everywhere. There is also a covered carport with a gate for …see more

from $70 / night

$350 / week

Book View

Responds fast!
avg. 3 hours 48 minutes

from $70 / night

9

Los Santos Province Vacation apartment rental

Los Santos Province / Pedasi

1 2 2 nights min

  • 1 bedroom
  • Sleeps 2
  • 2 nights min
  • Beach/lakeside relaxation
  • Child friendly
  • Air conditioning
Our property is located in the peaceful town of Pedasi, Los Santos, Panama, on the road to Playa Arenal, the most popular beach in town. Tortuga's Lodge has 5 apartment available to accommodate you for a nice stay. This unit is fully equipped with a complete kitchen, A/ …see more

from $60 / night

$320 / week

Book View

from $60 / night

(11) Very Good 

12

Vacation b&b with shared pool in Los Santos Province

Los Santos Province / Pedasi

5 2 1 night min

  • 5 bedrooms
  • Sleeps 2
  • 1 night min
  • Beach/lakeside relaxation
  • Nearest beach 4 mi
  • Swimming pool
Nestled in the heart of the folkloric Azuero peninsula, Casa Loma's Pedasi location offers country tranquility with many conveniences. Casa Loma is a Bed and Breakfast with individual rooms to rent for a night, a week, or longer (inquire about long term discounts), but …see more

from $50 / night

$350 / week

Book View

from $50 / night

18

Vacation home rental

Pedasi / Playa Venao

3 6 Min stay varies

  • 3 bedrooms
  • Sleeps 6
  • Min stay varies
  • Nearest beach 5 mi
  • Swimming pool
  • Child friendly
The House has 2 master bedrooms with private balconies and bathrooms equipped with Quality towels and linen Each room contains a Queen bed, Night stand,TV, AC ,Ceiling Fans and a small Safe for personal items. A third bedroom downstairs with 2 single beds. Large dinin …see more

from $225 / night

$1,575 / week

Book View

from $225 / night

(4) Excellent 

Certificate of Excellence

56

Vacation home in Los Santos Province

Los Santos Province / Las Tablas

1 2 2 nights min

  • 1 bedroom
  • Sleeps 2
  • 2 nights min
  • Beach/lakeside relaxation
  • Child friendly
  • Air conditioning
Enjoy Beach Life All Year Round in Panama at Uverito Beach! With the coming of fall, family and friends in Canada, U.S. and Europe find themselves thinking of the long, cold winter approaching. It's not just the ice and snow to cope with, but the enormous heating bills …see more

Certificate of Excellence

from $35 / night

$175 / week

Book View

Responds fast!
avg. 31 minutes

from $35 / night

(3) Excellent 

9

Apartment rental in Los Santos Province

Los Santos Province / Pedasi

1 2 2 nights min

  • 1 bedroom
  • Sleeps 2
  • 2 nights min
  • Child friendly
  • Car not necessary
  • Ask about pets
Our property is located in the peaceful town of Pedasi, Los Santos, Panama, on the road to Playa Arenal, the most popular beach in town. Tortuga's Lodge has 5 apartment available to accommodate you for a nice stay. This unit is fully equipped with a small kitchen, A/C, …see more

from $45 / night

$300 / week

Book View

from $45 / night

20

Vacation home in Los Santos Province

Los Santos Province / Pedasi

2 5 Min stay varies

  • 2 bedrooms
  • Sleeps 5
  • Min stay varies
  • Child friendly
  • Air conditioning
  • Private garden
Welcome to country living right outside of Pedasi! This beautiful home in an equestrian community in Limon, surrounded by forests. You are just a 5 minute drive from the charming village of Pedasi. There are several endless beaches just a short drive away. The village o …see more

from $70 / night

$350 - $525 / week

Book View

Responds fast!
avg. 3 hours 48 minutes

from $70 / night

(23) Very Good 

Certificate of Excellence

42

Las Tablas Vacation home rental

Los Santos Province / Las Tablas

2 4 2 nights min

  • 2 bedrooms
  • Sleeps 4
  • 2 nights min
  • Beach/lakeside relaxation
  • Nearest beach 0 mi
  • Child friendly
This 2-bedroom/2-bath beach house is located at Uverito Beach, Los Santos, Panama. The beach is literally at your footsteps. The beach house offers guests a unique layout and spectacular views up and down the coast. A large front porch offers plenty of space for relaxat …see more

Certificate of Excellence

from $55 / night

$225 / week

Book View

Responds fast!
avg. 31 minutes

from $55 / night

(1) Excellent 

9

Pedasi Vacation apartment rental

Los Santos Province / Pedasi

1 4 2 nights min

  • 1 bedroom
  • Sleeps 4
  • 2 nights min
  • Beach/lakeside relaxation
  • Child friendly
  • Air conditioning
Our property is located in the peaceful town of Pedasi, Los Santos, Panama, on the road to Playa Arenal, the most popular beach in town. Tortuga's Lodge has 5 apartment available to accommodate you for a nice stay. This unit is fully equipped with a small kitchen, A/C, …see more

from $90 / night

$360 / week

Book View

from $90 / night

(12) Very Good 

10

Los Santos Province Vacation b&b rental

Los Santos Province / Pedasi

1 4 1 night min

  • 1 bedroom
  • Sleeps 4
  • 1 night min
  • Beach/lakeside relaxation
  • Nearest beach 2 mi
  • Swimming pool
Pedasi Sports Club is one of the oldest Bed and Breakfasts and the oldest dive and fishing operation in Pedasi. Started in 2001 and moved to its current location in 2008 when the B&B opened, Pedasi Sports Club combines a 10 room Bed and Breakfast and an activities cent …see more

from $65 / night

$455 - $595 / week

Book View

from $65 / night

(1) Excellent 

15

Vacation home in Pedasi

Los Santos Province / Pedasi

2 4 Min stay varies

  • 2 bedrooms
  • Sleeps 4
  • Min stay varies
  • Beach/lakeside relaxation
  • Child friendly
  • Air conditioning
This is a 2 Bedroom 2 bath home just finished in 2014. Our home is walking distance from all the restaurants and less than a 5 minute drive to several local beaches. It is complete with granite counter-tops, stainless steel appliances, 2 refrigerators/freezers, COLD A/C …see more

from $90 / night

$550 / week

Book View

Responds fast!
avg. 3 hours 48 minutes

from $90 / night

(1) Excellent 

20

Vacation home in Los Santos Province

Los Santos Province / Pedasi

4 8 Min stay varies

  • 4 bedrooms
  • Sleeps 8
  • Min stay varies
  • Child friendly
  • Air conditioning
  • Private garden
Large comfortable home, suitable for large family or friends or couple who want more room. Great views, quiet area in village nice neighbors. Secure property with 5 car off road parking. 5 to 15 minutes drive from all beaches. 10 minutes walk to restaurants and shops. G …see more

from $150 / night

$800 - $1,150 / week

Book View

Responds fast!
avg. 3 hours 48 minutes

from $150 / night

19

Vacation home in Los Santos Province

Los Santos Province / Pedasi

2 4 Min stay varies

  • 2 bedrooms
  • Sleeps 4
  • Min stay varies
  • Child friendly
  • Air conditioning
  • Private garden
This home was just recently built and hardly even lived in! Comes with brand new appliances, nice wood touches throughout, and high ceilings. The space can accommodate 4 adults comfortably with 2 bedrooms and 2 1/2 baths. The living room has high quality furniture with …see more

from $100 / night

$600 / week

Book View

Responds fast!
avg. 3 hours 48 minutes

from $100 / night

24

Apartment accommodation in Los Santos Province with swimming pool

Pedasi / Destiladeros

1 4 Min stay varies

  • 1 bedroom
  • Sleeps 4
  • Min stay varies
  • Beach/lakeside relaxation
  • Nearest beach 0.2 mi
  • Swimming pool
Luxury granny unit in the "White Villa" in Los Destiladeros, Pedasi for 4 people max., private entrance, fully funished, one Double bed & two Single beds, fully equipped kitchen with gas stove, fridge, microwave , coffee maker, toaster, spacious living & dining area, S …see more

from $175 / night

$910 - $1,400 / week

Book View

Responds fast!
avg. 3 hours 5 minutes

from $175 / night

(5) Excellent 

23

Vacation guest house in Los Santos Province

Los Santos Province / Pedasi

1 2 2 nights min

  • 1 bedroom
  • Sleeps 2
  • 2 nights min
  • Air conditioning
  • Pet friendly
  • Private garden
Located only a couple minutes walk to town with restaurants, cantina's and groceries yet our setting is private and peaceful. Our home is fully furnished with a very comfy king bed. Everything is included, A/C, Internet, Sattelite TV, Hot Water, Washing machine and a re …see more

from $60 / night

$400 / week

Book View

from $60 / night

(1) Excellent 

19

Vacation home in Pedasi

Los Santos Province / Pedasi

2 4 Min stay varies

  • 2 bedrooms
  • Sleeps 4
  • Min stay varies
  • Child friendly
  • Air conditioning
  • Private garden
Welcome to your own private tropical paradise in Pedasi. This home sits on an oversized lot filled with fruit trees other beautiful plants. The home is completely fenced for your privacy and place to park. There are modern appliances, tv, and ac units! Just down the …see more

from $70 / night

$350 / week

Book View

Responds fast!
avg. 3 hours 48 minutes

from $70 / night

(1) Excellent 

29

Vacation home in Pedasi

Los Santos Province / Pedasi

2 8 2 nights min

  • 2 bedrooms
  • Sleeps 8
  • 2 nights min
  • Beach/lakeside relaxation
  • Child friendly
  • Air conditioning
Located on a prime hilltop, La Casona’s breathtaking view alone is priceless. The Colonial style architecture with high ceilings and thick walls combine luxury and solidity, inviting guests to feel comfortable and at home. Two equally spacious master bedrooms boast qu …see more

from $250 / night

$1,250 / week

Book View

from $250 / night

(3) Very Good 

57

Las Tablas Vacation home rental

Los Santos Province / Las Tablas

4 8 2 nights min

  • 4 bedrooms
  • Sleeps 8
  • 2 nights min
  • Beach/lakeside relaxation
  • Child friendly
The beach house has an absolutely amazing location, with daily sunrises over the ocean and sunsets off the back porch. The deck that overlooks the ocean is a spectacular place to spend your day, rocking on the hammock, eating your meals on the dining table, or reading a …see more

from $70 / night

$350 - $770 / week

Book View

Responds fast!
avg. 31 minutes

from $70 / night

(1) Excellent 

27

Los Santos Province Vacation villa accommodation

Pedasi / Destiladeros

5 12 Min stay varies

  • 5 bedrooms
  • Sleeps 12
  • Min stay varies
  • Swimming pool
  • Child friendly
  • Air conditioning
Luxury Design Villa in Playa Los Destiladeros, Pedasi fully furnished, total occupancy 12 people. 4 bed rooms, each with a full private bathroom, sleep up to 8. Independant granny, with private entrance, small kitchen, living & dining area, TV and full bathroom, sleeps …see more

from $850 / night

$4,750 - $5,225 / week

Book View

Responds fast!
avg. 3 hours 5 minutes

from $850 / night

19

Vacation home in Los Santos Province

Los Santos Province / Pedasi

2 4 Min stay varies

  • 2 bedrooms
  • Sleeps 4
  • Min stay varies
  • Child friendly
  • Air conditioning
  • Private garden
You will feel right at home in this beautiful 2 bedroom home in the heart of Pedasi. Each room in this house has an ac, although you probably won't need it as there are amazing breezes throughout the home. The master bedroom has a double bed, and the guest bedroom has 2 …see more

from $80 / night

$500 / week

Book View

Responds fast!
avg. 3 hours 48 minutes

from $80 / night

17

Vacation home in Pedasi

Los Santos Province / Pedasi

2 5 Min stay varies

  • 2 bedrooms
  • Sleeps 5
  • Min stay varies
  • Child friendly
  • Air conditioning
  • Private garden
Beautiful, new two bedroom duplex home in Pedasi with custom finishes throughout. Open living area with a lot of natural light. House is equipped with everything you need to make you feel at home! Internet, satellite tv, AC's in both rooms and living room. House is …see more

from $90 / night

$550 / week

Book View

Responds fast!
avg. 3 hours 48 minutes

from $90 / night

6

Vacation b&b with shared pool in Pedasi

Los Santos Province / Pedasi

1 5 1 night min

  • 1 bedroom
  • Sleeps 5
  • 1 night min
  • Swimming pool
  • Child friendly
  • Air conditioning
Nestled in the heart of the folkloric Azuero peninsula, Casa Loma's Pedasi location offers country tranquility with many conveniences. Casa Loma is a Bed and Breakfast with individual rooms to rent for a night, a week, or longer (inquire about long term discounts), but …see more

from $85 / night

$550 - $760 / week

Book View

from $85 / night

42

Vacation apartment in Cambutal

Los Santos Province / Cambutal

1 4 1 night min

  • 1 bedroom
  • Sleeps 4
  • 1 night min
  • Nearest beach 0 mi
  • Child friendly
  • Car not necessary
Deluxe loft apartment nestled deep in the interior of Panama near a sleepy little fishing village right on a spectacular natural Pacific Ocean Beach, it's actually your front yard that you can walk for miles east or west sometimes not seeing another person. Fully furnis …see more

from $150 / night

$500 / week

Book View

from $150 / night

(1) Excellent 

41

Vacation guest house in Los Santos Province

Pedasi / Playa Venao

1 4 Min stay varies

  • 1 bedroom
  • Sleeps 4
  • Min stay varies
  • Beach/lakeside relaxation
  • Nearest beach 9 mi
  • Child friendly
*Fully Furnished 750 sq/ft (49 sq/mts) *One large queen bedroom with A/C, dresser, chair, table, lamps *One full bath with walk in rain head shower , storage * Living/Kitchen combo, and large closet. Queen hide a bed in Living area that sleeps 2 adults or 3 children …see more

from $55 / night

$350 / week

Book View

from $55 / night

5

Vacation b&b with shared pool in Los Santos Province

Los Santos Province / Pedasi

1 4 1 night min

  • 1 bedroom
  • Sleeps 4
  • 1 night min
  • Swimming pool
  • Child friendly
  • Air conditioning
Nestled in the heart of the folkloric Azuero peninsula, Casa Loma's Pedasi location offers country tranquility with many conveniences. Casa Loma is a Bed and Breakfast with individual rooms to rent for a night, a week, or longer (inquire about long term discounts), but …see more

from $85 / night

$550 - $690 / week

Book View

from $85 / night

17

Vacation home rental

Los Santos Province / Pedasi

2 4 Min stay varies

  • 2 bedrooms
  • Sleeps 4
  • Min stay varies
  • Child friendly
  • Air conditioning
  • Private garden
Come get lost in our beautiful village called Pedasi. During the day, walk through town and visit with the friendly locals. You can bike or drive to the closest beach to swim or just watch the local fisherman come in with their catch of the day! At night, head to the to …see more

from $75 / night

$400 / week

Book View

Responds fast!
avg. 3 hours 48 minutes

from $75 / night

(1)  

5

Vacation b&b with shared pool in Los Santos Province

Los Santos Province / Pedasi

1 2 1 night min

  • 1 bedroom
  • Sleeps 2
  • 1 night min
  • Swimming pool
  • Child friendly
  • Air conditioning
Pedasi Sports Club is one of the oldest Bed and Breakfasts and the oldest dive and fishing operation in Pedasi. Started in 2001 and moved to its current location in 2008 when the B&B opened, Pedasi Sports Club combines a 10 room Bed and Breakfast and an activities cent …see more

from $70 / night

$450 / week

Book View

from $70 / night

5

Vacation b&b rental

Los Santos Province / Pedasi

1 3 1 night min

  • 1 bedroom
  • Sleeps 3
  • 1 night min
  • Swimming pool
  • Child friendly
  • Air conditioning
Nestled in the heart of the folkloric Azuero peninsula, Casa Loma's Pedasi location offers country tranquility with many conveniences. Casa Loma is a Bed and Breakfast with individual rooms to rent for a night, a week, or longer (inquire about long term discounts), but …see more

from $65 / night

$410 - $480 / week

Book View

from $65 / night

18

Vacation home in Los Santos Province

Los Santos Province / Pedasi

2 4 Min stay varies

  • 2 bedrooms
  • Sleeps 4
  • Min stay varies
  • Child friendly
  • Private garden
This is a two bedroom one bath home in the quaint town of Pedasi. It is stocked with what you need to make your stay here comfortable. There is a private backyard with grass, trees and a covered patio. There is parking for one car and a sidewalk to access the front door …see more

from $70 / night

$350 / week

Book View

Responds fast!
avg. 3 hours 48 minutes

from $70 / night

(1) Good 

19

Vacation villa in Pedasi

Los Santos Province / Pedasi

1 4 2 nights min

  • 1 bedroom
  • Sleeps 4
  • 2 nights min
  • Beach/lakeside relaxation
  • Child friendly
Ocean loft 14 is a boutique experience ideal for those seeking a retreat without sacrificing luxury. Hidden in Los Destiladeros beach, twenty minutes from Pedasí's center, ocean loft 14 is an end unit located on the most intimate corner of the Azuero's gated community. …see more

from $195 / night

$1,170 / week

Book View

from $195 / night

19

Home rental in Pedasi

Los Santos Province / Pedasi

1 7 Min stay varies

  • 1 bedroom
  • Sleeps 7
  • Min stay varies
  • Child friendly
  • Air conditioning
This ocean loft is just a few minutes walk to the beautiful Playa Los Destiladeros. You'll have the convenience of spending your days at the beach from sunrise to sunset! The home is fully stocked with what you need for your convenience. There are three queen beds up …see more

from $90 / night

$550 - $1,075 / week

Book View

Responds fast!
avg. 3 hours 48 minutes

from $90 / night

30

Private room rental in Los Santos Province

Los Santos Province / Las Tablas

6 16 1 night min

  • 6 bedrooms
  • Sleeps 16
  • 1 night min
  • Nearest beach 7 mi
  • Child friendly
  • Car not necessary
We want our home to be a retreat for you, your family, friend (s) or travel companion. Our venture into the growing entrepreneur business of home-based businesses began in February 2008 when we moved to Santo Domingo, the land of our roots and heritage.We have been pers …see more

from $38 / night

$266 / week

Book View

Responds fast!
avg. 43 minutes

from $38 / night

48

Vacation home in Los Santos Province

Los Santos Province / Cambutal

2 8 7 nights min

  • 2 bedrooms
  • Sleeps 8
  • 7 nights min
  • Nearest beach 0 mi
  • Child friendly
  • Car not necessary
FULLY FURNISHED! 2 LARGE BEDROOMS each with air conditioner and ceiling fan, master has teak queen size bed/large ocean theme bathroom, hot water, walk-in closet, dresser drawers and satellite TV; guest bedroom has one queen and one full bed, closet, nice custom dolph …see more

from $143 / night

$1,000 / week

Book View

from $143 / night

(1) Very Good 

13

Vacation home rental

Los Santos Province / Pedasi

3 6 2 nights min

  • 3 bedrooms
  • Sleeps 6
  • 2 nights min
  • Swimming pool
  • Child friendly
  • Air conditioning
Luxurious Home on secluded beachfront located on the Pacific Ocean. Prepare to relax and enjoy the sun and sounds of the ocean! Sleeps 6. Three Bedrooms, each with en-suite bath and walk in closet, Master Bdrm has Jacuzzi tub. Den with adjoining half bath, fully equ …see more

from $450 / night

$2,800 / week

Book View

Responds fast!
avg. 1 hour 12 minutes

from $450 / night

(1) Excellent 

27

Los Santos Province Vacation condo rental

Los Santos Province / Pedasi

1 5 3 nights min

  • 1 bedroom
  • Sleeps 5
  • 3 nights min
  • Beach/lakeside relaxation
  • Nearest beach 0 mi
  • Swimming pool
This beautiful two-story, air-conditioned vacation loft is located steps from the nearly-secluded, gorgeous Playa Destiladeros and Amaretto Restaurant and Bar. The loft has a queen-sized bed and full bathroom with a shower located on the first floor. The second floor …see more

from $125 / night

$750 - $1,175 / week

Book View

Responds fast!
avg. 2 hours 31 minutes

from $125 / night

11

Vacation beach hut rental

Los Santos Province / Cambutal

2 7 1 night min

  • 2 bedrooms
  • Sleeps 7
  • 1 night min
  • Beach/lakeside relaxation
  • Nearest beach 1 mi
  • Child friendly
Cambutal Housing is a break with the sea and the motaña between you and nature, with family or with your partner. From an ecological natural (renewable energy solar panels and natural spring water) and exceptional privacy. From desobar see turtles in front of you almost …see more

from $180 / night

$1,200 / week

Book View

from $180 / night