50 Best Edisto Island Vacation rentals on Holiday Lettings - Beach rentals

Close

View larger map

Edisto Island

No dates Enter dates for accurate prices -

Adults, Children

Enter dates for more accurate prices

Payment Protection
To book this vacation rental you need to pay through the Holiday Lettings website. We can’t protect your payment if you don’t pay through us. Learn more

594 Vacation rentals

(3) Excellent 

32

Edisto Island Vacation home rental

Coastal South Carolina / Edisto Island

4 9 1 night min

  • 4 bedrooms
  • Sleeps 9
  • 1 night min
  • Child friendly
  • Air conditioning
  • Ask about pets
4BR / 2BA (3Q, Bunk, S) - Sleeps 9 - This home is on the corner of Myrtle and Jenkins St and a short walk to a beach access. "Takin' It 'Sto" has beautiful hardwood floors for easy maintenance. There are pretty oak trees in the front and back of the property. You enter …see more

from $149 / night

$895 - $1,550 / week

Inquire View

from $149 / night

29

Vacation home in Edisto Island

Coastal South Carolina / Edisto Island

4 12 1 night min

  • 4 bedrooms
  • Sleeps 12
  • 1 night min
  • Child friendly
  • Air conditioning
  • Ask about pets
4BR / 2BA - (2K, 2TripleBunks, 2S) - Sleeps 12 -This beach walk home is located on quiet Myrtle Street. Overlooking the bike path and a short walk to a beach access on the St Helena Sound. You are just a 1/2 block to the Lions Club for summer Bingo fun. This home ope …see more

from $145 / night

$875 - $1,695 / week

Inquire View

from $145 / night

(1) Excellent 

37

Edisto Island Vacation home rental

Coastal South Carolina / Edisto Island

4 9 1 night min

  • 4 bedrooms
  • Sleeps 9
  • 1 night min
  • Ask about children
  • Air conditioning
  • Pet friendly
4BR / 2BA - (Q, D, 5S) - Sleeps 9 - Recent upgrades make this classic, older beach front cottage, very nice and comfortable and an excellent value. Located right on the St. Helena Sound, enjoy the lovely sunsets & extra large screen porch. This property has a central l …see more

from $165 / night

$995 - $2,895 / week

Inquire View

from $165 / night

(1) Excellent 

28

Vacation home in Edisto Island

Coastal South Carolina / Edisto Island

4 12 1 night min

  • 4 bedrooms
  • Sleeps 12
  • 1 night min
  • Child friendly
  • Ask about pets
4BR +Loft / 3BA (K, Q, Q, Q/S, D/Trundle) - Sleeps 12 -The home is located on quiet Seaview Lane with limited water views from the porches. Seaview Lane is the first block behind Palmetto Blvd and is not a through street. A covered porch with swings faces Seaview Lane …see more

from $150 / night

$900 - $2,000 / week

Inquire View

from $150 / night

(1) Excellent 

32

Edisto Island Vacation home rental

Coastal South Carolina / Edisto Island

4 12 1 night min

  • 4 bedrooms
  • Sleeps 12
  • 1 night min
  • Child friendly
  • Air conditioning
  • Pet friendly
4BR + Den / 4BA (1K, 2Q, 2S + trundles, SS) -Sleeps 12 - This outstanding beach front house is beautifully decorated and appointed with everything you need for a perfect Edisto Beach vacation. The first floor has a large open floor plan including the living, dining an …see more

from $415 / night

$2,495 - $6,150 / week

Inquire View

from $415 / night

35

Edisto Island Vacation home rental

Coastal South Carolina / Edisto Island

3 6 1 night min

  • 3 bedrooms
  • Sleeps 6
  • 1 night min
  • Ask about children
  • Air conditioning
  • Ask about pets
3BR / 2BA (2Q, 2S) - Sleeps 6 - Located on the corner of Atlantic and Pompano St this home is just 1 house to Palmetto Blvd and straight across to a beach access. A very easy walk to the beach and you even have ocean views from the deck! This home has a large wrap arou …see more

from $149 / night

$895 - $1,295 / week

Inquire View

from $149 / night

(1) Excellent 

25

Edisto Island Vacation home rental

Coastal South Carolina / Edisto Island

3 11 1 night min

  • 3 bedrooms
  • Sleeps 11
  • 1 night min
  • Swimming pool
  • Child friendly
  • Air conditioning
3BR + LOFT / 3.5BA - (K, D+S, D , 2S, Sleeper Sofa) - Sleeps 11 - Located in a quiet residential neighborhood in the Wyndham Ocean Ridge Resort this property is on the right side of a large duplex with plenty of parking for the entire family. You are also close to the …see more

from $125 / night

$750 - $1,695 / week

Inquire View

from $125 / night

28

Edisto Island Vacation home rental

Coastal South Carolina / Edisto Island

4 12 1 night min

  • 4 bedrooms
  • Sleeps 12
  • 1 night min
  • Child friendly
  • Air conditioning
  • Ask about pets
4BR + Den / 4BA - (2Q, 4D) Sleeps 12 - Directly across from a beach access and on the beachside of Palmetto this home has outstanding views of the ocean. A nice open floor plan allows you to enjoy the breezes at "Ocean Breeze". This home opens into a foyer with a short …see more

from $215 / night

$1,295 - $2,695 / week

Inquire View

from $215 / night

21

Edisto Island Vacation home rental

Coastal South Carolina / Edisto Island

4 10 1 night min

  • 4 bedrooms
  • Sleeps 10
  • 1 night min
  • Ask about children
  • Air conditioning
  • Ask about pets
4BR / 3.5 BA (K, 2Q, 2S, SS) -Sleeps 10 - A very nice creekfront home located on quiet Jungle Shores Drive. Enjoy the sunsets and wildlife while relaxing on the large screen porch. You have your own privated dock for crabbing or fishing (remember that the Yacht Basin is …see more

from $175 / night

$1,050 - $2,250 / week

Inquire View

from $175 / night

41

Vacation home in Edisto Island

Coastal South Carolina / Edisto Island

4 11 1 night min

  • 4 bedrooms
  • Sleeps 11
  • 1 night min
  • Child friendly
  • Air conditioning
  • Pet friendly
4BR / 2BA - Sleeps 11 - 3Q, Single, Bunk, Sleeper - Spacious, family friendly home with lots of sunlight are just a few ways to describe this beach walk home. The extra large sundeck has many seating areas and a boardwalk to the rear of the house and the kitchen door. …see more

from $125 / night

$750 - $1,995 / week

Inquire View

from $125 / night

22

Edisto Island Vacation home rental

Coastal South Carolina / Edisto Island

5 12 1 night min

  • 5 bedrooms
  • Sleeps 12
  • 1 night min
  • Child friendly
  • Air conditioning
  • Ask about pets
5BR + Den/ 4BA (K, 3Q, 2D, SS) - Sleeps 12 - This beautiful home is locate on quiet Arc St and is only 1/2 block to the beach! You have great views from the upper decks and each bedroom opens onto a porch. A nice living, dining, and kitchen combination faces Arc St. A c …see more

from $182 / night

$1,095 - $2,750 / week

Inquire View

from $182 / night

(1) Excellent 

29

Home rental in Edisto Island

Coastal South Carolina / Edisto Island

7 18 1 night min

  • 7 bedrooms
  • Sleeps 18
  • 1 night min
  • Child friendly
  • Air conditioning
  • Ask about pets
7BR / 6.5BA- Sleeps 17 (3K, 2Q, D, 1S, 2 Double , 2 Bunk) "View Pointe" is a home decorated in a style that offers comfort and elegance, reflective of the love that this longtime Edisto Beach homeowner has. This home has everything one could hope for. As you enter the …see more

from $564 / night

$3,950 - $8,150 / week

Inquire View

from $564 / night

(1) Excellent 

18

Vacation home in Edisto Island

Coastal South Carolina / Edisto Island

6 14 1 night min

  • 6 bedrooms
  • Sleeps 14
  • 1 night min
  • Child friendly
  • Air conditioning
  • Ask about pets
6 BR / 6 BA (K, 4Q, 4S) - Sleeps 14 - This large comfortable home is an easy walk up Lybrand St to a beach access. There is lots of room inside and out for a big family gathering. A covered porch, facing Lybrand, has lots of rockers for relaxing after a day on the beach …see more

from $215 / night

$1,295 - $3,395 / week

Inquire View

from $215 / night

26

Vacation home in Edisto Island

Coastal South Carolina / Edisto Island

2 4 1 night min

  • 2 bedrooms
  • Sleeps 4
  • 1 night min
  • Child friendly
  • Air conditioning
  • Ask about pets
2BR / 2BA - Sleeps 4 - Queen, 2 Twins - Located at the end of Oyster Factory Road on Edisto Island, just a few minutes away from the first beach access (about 5 miles from house to beach). This charming creek front cottage is so charming that you won't want the leave. …see more

from $165 / night

$995 - $1,550 / week

Inquire View

from $165 / night

22

Edisto Island Vacation home rental

Coastal South Carolina / Edisto Island

4 10 1 night min

  • 4 bedrooms
  • Sleeps 10
  • 1 night min
  • Child friendly
  • Air conditioning
  • Pet friendly
4BR / 3.5BA - Sleeps 10 - K, 2Q, Bunk, 2Day Beds. - A unique custom home in Jeremy Cay. The home is just a short walk to the beach access but the beach views from the top floor is outstanding!! The Main House has an entrance foyer, large open great room with the living …see more

from $365 / night

$2,195 - $3,995 / week

Inquire View

from $365 / night

22

Vacation home in Edisto Island

Coastal South Carolina / Edisto Island

4 10 1 night min

  • 4 bedrooms
  • Sleeps 10
  • 1 night min
  • Child friendly
  • Air conditioning
  • Pet friendly
4BR / 3BA - K, 2Q, 2Bunks - Sleeps 10 – The home is spacious and inviting, evoking coastal fun and relaxation “Down River”. While you are unpacking your car, you will hear the ocean waves serenading you from across the street where the beach access is located. Sit a s …see more

from $165 / night

$995 - $2,495 / week

Inquire View

from $165 / night

20

Vacation villa with shared pool in Edisto Island

Coastal South Carolina / Edisto Island

2 6 1 night min

  • 2 bedrooms
  • Sleeps 6
  • 1 night min
  • Swimming pool
  • Child friendly
  • Air conditioning
2BR /2BA - Sleeps 6 - K, Q. SS - Located in Wyndham Ocean Ridge on the 2nd floor overlooking the golf course. The best view of the golf course from this updated villa. Enter the central hallway with the kitchen tucked to the side and a full view out the living area slid …see more

from $158 / night

$950 - $1,250 / week

Inquire View

from $158 / night

(5) Excellent 

18

Home rental in Edisto Island

Coastal South Carolina / Edisto Island

4 12 1 night min

  • 4 bedrooms
  • Sleeps 12
  • 1 night min
  • Child friendly
  • Air conditioning
  • Pet friendly
4BR / 2BA - (2K, 1Q, 2 sets of Bunks,Q SS) - Sleeps 12 - This well-maintained oceanfront home is as close to the beach as you can get! Amazing views of the Atlantic from many vantage points in this property. The home is nicely furnished and decorated in relaxing coastal …see more

from $335 / night

$2,350 - $4,995 / week

Inquire View

from $335 / night

30

Home rental in Edisto Island

Coastal South Carolina / Edisto Island

4 8 1 night min

  • 4 bedrooms
  • Sleeps 8
  • 1 night min
  • Child friendly
  • Air conditioning
  • Ask about pets
4BR / 3BA - Sleeps 10 - 3Q, Bunk - What a perfect location - within walking distance to the Edisto Marina and a short bike ride to the nearest beach access. The first two floors of this townhouse have everything you will need for a perfect Edisto vacation. (top floor is …see more

from $315 / night

$1,895 - $3,195 / week

Inquire View

from $315 / night

29

Edisto Island Vacation home rental

Coastal South Carolina / Edisto Island

2 6 1 night min

  • 2 bedrooms
  • Sleeps 6
  • 1 night min
  • Child friendly
  • Air conditioning
  • Ask about pets
2BR / 1BA - (2 Queens, Sleeper) -Sleeps 6 - A cute beach view cottage with nice water views on a quiet side street. Cozy is the best way to describe this 2nd floor apartment. Only 4 houses from the beach access. You enter a room that is combination living area and glass …see more

from $108 / night

$650 - $1,025 / week

Inquire View

from $108 / night

(1) Excellent 

29

Home rental in Edisto Island

Coastal South Carolina / Edisto Island

4 10 1 night min

  • 4 bedrooms
  • Sleeps 10
  • 1 night min
  • Child friendly
  • Air conditioning
  • Pet friendly
4BR / 4BA (2K, Q, Bunk, S, Cot) - Sleeps 10 - Looking for privacy and an easy walk to the beach, then "Tree Tops" will satisfy your beach vacation needs. This home sits at the end of Pompano St with no thru traffic. A large open deck connects to a screen porch facing P …see more

from $157 / night

$945 - $1,900 / week

Inquire View

from $157 / night

27

Vacation home in Edisto Island

Coastal South Carolina / Edisto Island

5 13 1 night min

  • 5 bedrooms
  • Sleeps 13
  • 1 night min
  • Child friendly
  • Air conditioning
  • Pet friendly
5BR / 3BA - Sleeps 13 - K, 2Q, 2S, Double/Double Trundle/1S - Sleeps 13 - This duplex unit, located on the corner of Dawhoo St and Jungle Shores Dr, is just a short walk to the beach. There is plenty of parking for a boat or cars. The main level has the great room (livi …see more

from $165 / night

$995 - $2,295 / week

Inquire View

from $165 / night

32

Vacation home in Edisto Island

Coastal South Carolina / Edisto Island

3 8 1 night min

  • 3 bedrooms
  • Sleeps 8
  • 1 night min
  • Ask about children
  • Air conditioning
  • Pet friendly
3BR / 2BA (K, Q, TB, S) - Sleeps 8 - A comfortable beach walk home that is located on the corner of Jungle Rd and Dawhoo St. You have the largest lagoon on Edisto Beach right at your back door. A great place to fish and crab and just one block to the beach! You will hav …see more

from $132 / night

$795 - $1,495 / week

Inquire View

from $132 / night

17

Vacation home in Edisto Island

Coastal South Carolina / Edisto Island

4 8 1 night min

  • 4 bedrooms
  • Sleeps 8
  • 1 night min
  • Child friendly
  • Air conditioning
  • Ask about pets
4BR / 2BA - 2K, Q, D, S - Sleeps 8 - This quiet, cozy vacation home is located just a 1/2 block to the beach. You will enter the home from the large, well furnished screen porch into the great room. A skylight brings in nice natural light into this space. There are 2 b …see more

from $99 / night

$695 - $1,200 / week

Inquire View

from $99 / night

21

Vacation home rental

Coastal South Carolina / Edisto Island

4 12 1 night min

  • 4 bedrooms
  • Sleeps 12
  • 1 night min
  • Child friendly
  • Air conditioning
  • Ask about pets
4BR + Loft / 3BA - (K, 1Q, 1D, 2S, Trundle, SS) -Sleeps 12 - Everyone wants to stay on Pompano Street - close enough to the beach but quiet. Bright & sunny best describes this home. 2 large covered decks greet you as you pull up to an oversized yard with plenty of co …see more

from $149 / night

$895 - $1,895 / week

Inquire View

from $149 / night

35

Vacation home in Edisto Island

Coastal South Carolina / Edisto Island

4 11 1 night min

  • 4 bedrooms
  • Sleeps 11
  • 1 night min
  • Child friendly
  • Air conditioning
  • Ask about pets
4BR / 2 BA - (2Q, 2D, S, SS) - Sleeps 11- 2nd Row classic Edisto beach cottage located on Palmetto Blvd with great water views across Palmetto Blvd. The house has the charm of tongue n' groove pine walls, floors, ceilings - a real beach cottage. When you get to the hous …see more

from $141 / night

$850 - $1,495 / week

Inquire View

from $141 / night

(2) Excellent 

18

Vacation home rental

Coastal South Carolina / Edisto Island

4 10 1 night min

  • 4 bedrooms
  • Sleeps 10
  • 1 night min
  • Swimming pool
  • Child friendly
  • Air conditioning
4BR / 2BA (K, 2Q, 1S+Trundle, Bunk)- Sleeps 10 - Only the second house after you turn onto Oristo Ridge, this nicely furnished home is just a short walk to the back gate of the Ocean Ridge Resort with beach access just 2 blocks away. You enter this home from a covered …see more

from $183 / night

$1,100 - $1,750 / week

Inquire View

from $183 / night

12

Vacation villa with shared pool in Edisto Island

Coastal South Carolina / Edisto Island

1 7 1 night min

  • 1 bedroom
  • Sleeps 7
  • 1 night min
  • Swimming pool
  • Child friendly
  • Air conditioning
1BR + Sleeping Loft / 1BA - Sleeps 7 - King, Single, Double, Sleeper - Wonderful views from this 3rd floor villa of the Plantation Golf Course, and even of Big Bay Creek. A very nice villa with an open great room, There is a spiral staircase in the corner of dining area …see more

from $104 / night

$625 - $695 / week

Inquire View

from $104 / night

20

Vacation home in Edisto Island

Coastal South Carolina / Edisto Island

5 8 1 night min

  • 5 bedrooms
  • Sleeps 8
  • 1 night min
  • Ask about children
  • Air conditioning
  • Ask about pets
4BR / 3BA - Sleeps 10 - K, Q, 2S, 2D- This property is a boater's dream! You share a boat ramp but have your own private dock and gazebo overlooking the Edisto tidal marina yacht basin. There is a nice sitting area under the house complete with swings overlooking the ti …see more

from $199 / night

$1,195 - $2,195 / week

Inquire View

from $199 / night

29

Vacation home in Edisto Island

Coastal South Carolina / Edisto Island

4 8 1 night min

  • 4 bedrooms
  • Sleeps 8
  • 1 night min
  • Ask about children
  • Air conditioning
  • Ask about pets
4 Br / 2 BA (3Q, 2S) - Sleeps 8 - A comfortable beach view home in a secluded yard, only one house from the corner of Mitchell St and Palmetto Blvd. You will enter the home from a small side deck into the kitchen of this home. An eating bar separates the kitchen from th …see more

from $121 / night

$850 - $1,395 / week

Inquire View

from $121 / night

22

Vacation home in Edisto Island

Coastal South Carolina / Edisto Island

4 10 1 night min

  • 4 bedrooms
  • Sleeps 10
  • 1 night min
  • Ask about children
  • Air conditioning
  • Ask about pets
4BR / 2BA (2Q, 3D, Single) - Sleeps 11 - Renovated Spring 2018! It is all about the views from this home across Palmetto Blvd from the beach. As you enter from the rear steps you walk into the Great Room. There is also a set of stairs on the Palmetto Blvd side of the h …see more

from $133 / night

$799 - $2,050 / week

Inquire View

from $133 / night

21

Edisto Island Vacation home rental

Coastal South Carolina / Edisto Island

4 8 1 night min

  • 4 bedrooms
  • Sleeps 8
  • 1 night min
  • Child friendly
  • Air conditioning
  • Ask about pets
4BR/2 1/2BA - Sleeps 8 (2Q,4S) - Sleeps 8 - This nice beach walk property is located at the end of Seabrook St on a shady lot. A quiet location to come and relax on Edisto! This homeowner has provided many details to make your stay enjoyable, such as extra fans for o …see more

from $142 / night

$995 - $1,750 / week

Inquire View

from $142 / night

19

Home rental in Edisto Island

Coastal South Carolina / Edisto Island

4 8 1 night min

  • 4 bedrooms
  • Sleeps 8
  • 1 night min
  • Child friendly
  • Air conditioning
  • Pet friendly
4BR / 2.5 BA (K, 3Q) - Sleeps 8 - Come enjoy the sunsets over the marsh and Scott Creek! This charming house is just a short block walk to the beach and right on the bike path. Jungle Shores is a sandy road just beyond Jungle Road a little bit off the beaten path but c …see more

from $158 / night

$950 - $2,295 / week

Inquire View

from $158 / night

(2) Very Good 

21

Vacation villa rental

Coastal South Carolina / Edisto Island

2 6 1 night min

  • 2 bedrooms
  • Sleeps 6
  • 1 night min
  • Swimming pool
  • Child friendly
  • Air conditioning
2BR / 2BA - Sleeps 6 - King, Queen, Sleeper - Outstanding, sun filled cottage with great golf views from the glassed porch. Close to the main entrance in Wyndham Ocean Ridge so there is easy access getting to the beach, marina, bike path. Private sundeck overlooking …see more

from $125 / night

$750 - $950 / week

Inquire View

from $125 / night

(1) Excellent 

22

Vacation villa with shared pool in Edisto Island

Coastal South Carolina / Edisto Island

3 8 1 night min

  • 3 bedrooms
  • Sleeps 8
  • 1 night min
  • Swimming pool
  • Ask about children
  • Pet friendly
2BR + Loft / 2BA - K, Q, 2S in loft / SS - Wow! Beautiful corner villa with great views of the lagoon & wildlife. Closest villa to the walking gate out to the marina and an easy bike ride to the beach or to just cruise around the beach. The open great room (living, di …see more

from $156 / night

$1,095 - $1,495 / week

Inquire View

from $156 / night

22

Vacation villa with shared pool in Edisto Island

Coastal South Carolina / Edisto Island

2 6 1 night min

  • 2 bedrooms
  • Sleeps 6
  • 1 night min
  • Swimming pool
  • Child friendly
  • Air conditioning
2BR / 2BA - Sleeps 6 - (Q, 2S, SS) - Marsh views, Sunset Views, River Views, Marina Views and don't forget to catch the dolphins as they come up the creek for dinner. A well appointed and very comfortable 2nd floor villa. As you enter the 2nd floor villa, the guest b …see more

from $125 / night

$750 - $950 / week

Inquire View

from $125 / night

23

Edisto Island Vacation home rental

Coastal South Carolina / Edisto Island

4 10 1 night min

  • 4 bedrooms
  • Sleeps 10
  • 1 night min
  • Child friendly
  • Air conditioning
  • Pet friendly
4BR/3BA - Sleeps 10 (3Q, 2 Bunks) - Sleeps 10 - A nice beach walk home located on popular Pompano St. Just a short walk to a beach access from this property. You will enter the "Ellis House" through a screen porch facing Pompano. There is an open deck area on either …see more

from $213 / night

$1,495 - $1,795 / week

Inquire View

from $213 / night

(2) Very Good 

11

Edisto Island Vacation home rental

Coastal South Carolina / Edisto Island

1 4 1 night min

  • 1 bedroom
  • Sleeps 4
  • 1 night min
  • Child friendly
  • Air conditioning
  • Pet friendly
1BR / 1.5BA (Q, 2S) - Sleeps 4 - You have found the perfect spot for a small family. The top floor of the "Jordan House" is the sport. This apartment is only two houses from and across the street from a beach access for St Helena Sound. Perfect for a couple or small fam …see more

from $70 / night

$425 - $695 / week

Inquire View

from $70 / night

15

Home rental in Edisto Island

Coastal South Carolina / Edisto Island

4 12 1 night min

  • 4 bedrooms
  • Sleeps 12
  • 1 night min
  • Child friendly
  • Air conditioning
  • Ask about pets
4BR + Den/ 4.5 BA - ( 2K, Q, 2D, TR) - Sleeps 12 - Just a short walk to the beach from this quiet side street, this home has everything needed for a perfect Edisto Beach vacation. Enter the home from the covered front porch right into a wide front hall with a 1/2 bath …see more

from $242 / night

$1,695 - $2,450 / week

Inquire View

from $242 / night

(1) Excellent 

30

Home rental in Edisto Island

Coastal South Carolina / Edisto Island

6 14 1 night min

  • 6 bedrooms
  • Sleeps 14
  • 1 night min
  • Ask about children
  • Air conditioning
  • Ask about pets
6BR / 6BA (3K, 3Q, 2S plus trundle) - Sleeps 14 - This beach front home is in a prime location on Point St., as if this was not enough for a fabulous vacation, you will find the home beautifully decorated with some of the best ocean views anywhere on Edisto! The main l …see more

from $499 / night

$2,995 - $7,950 / week

Inquire View

from $499 / night