50 Best Isle of Palms Vacation rentals on Holiday Lettings - Beach rentals

Close

Isle of Palms

No dates Enter dates for accurate prices -

Adults, Children

Enter dates for more accurate prices

Payment Protection
To book this vacation rental you need to pay through the Holiday Lettings website. We can’t protect your payment if you don’t pay through us. Learn more

209 Vacation rentals

24

Apartment rental in Isle of Palms with shared pool

Coastal South Carolina / Isle of Palms

3 8 Min stay varies

  • 3 bedrooms
  • Sleeps 8
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
Easy Breezy Beachy! Welcome to paradise! “The Seascape at 512” is a stunning three bedroom, three bath condominium located in the exclusive Wild Dunes resort. Extensive renovations and professional décor, with no expense spared, make this property a true gem. Enjoy …see more

from $520 / night

$1631 - $4108 / week

Book View

from $520 / night

(2) Excellent 

27

Home rental in Isle of Palms

Coastal South Carolina / Isle of Palms

4 12 Min stay varies

  • 4 bedrooms
  • Sleeps 12
  • Min stay varies
  • Beach/lakeside relaxation
  • Nearest beach 0 mi
  • Child friendly
Partial ocean views from top floor master bedroom * Spacious screened-in back patio * Less than 240 steps to the beach * 1 block from Isle of Palms Recreational Center ... Yes, this house looks unique because it is - 2 homes in 1 and 3 floors! Cameron's Skybox is loca …see more

from $225 / night

$2002 - $2940 / week

Book View

from $225 / night

24

Vacation apartment with shared pool in Isle of Palms

Coastal South Carolina / Isle of Palms

3 8 Min stay varies

  • 3 bedrooms
  • Sleeps 8
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
Look no further than “A Finer View” at Mariner’s Walk 11-E to find a relaxing vacation destination! This well-appointed condominium is uniquely designed with three levels, offering oceanfront views from not only the living area, but also two bedrooms! Featuring accomm …see more

from $472 / night

$1390 - $3406 / week

Book View

from $472 / night

(14) Very Good 

13

Vacation apartment rental

Coastal South Carolina / Isle of Palms

1 4 Min stay varies

  • 1 bedroom
  • Sleeps 4
  • Min stay varies
  • Beach/lakeside relaxation
  • Swimming pool
  • Child friendly
These vacation rentals are 1 BR/1BA Condos (first and third floor units) conveniently located on ocean near shopping, restaurants, & grocery store. Each condo is very nicely decorated and expertly maintained. A fishing pier & swimming pool are available for our guests. …see more

from $97 / night

$555 - $1127 / week

Book View

from $97 / night

25

Isle of Palms Vacation home rental

Coastal South Carolina / Isle of Palms

4 8 Min stay varies

  • 4 bedrooms
  • Sleeps 8
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
Beachwood West 23 is a classic beach house featuring two master bedrooms, heart of pine floors, a modern kitchen and many amenities. This comfortable home enjoys a private lot shaded by 100 year old oak trees. Cul de sac location near quiet residential beach. 4 bedrooms …see more

from $324 / night

$1076 - $2803 / week

Book View

from $324 / night

(9) Very Good 

24

Vacation villa in Isle of Palms

Coastal South Carolina / Isle of Palms

3 8 Min stay varies

  • 3 bedrooms
  • Sleeps 8
  • Min stay varies
  • Beach/lakeside relaxation
  • Nearest beach 0.16 mi
  • Swimming pool
Included in Price: Spacious 3 Bedroom, 2.5 bath villa, High-speed golf cart that seats 5, wagon that connects to golf cart to transport beach items, 2 kayaks, 4 adult bikes, 4 children's bikes, one hot-wheel, gas grill, coolers, floats, boogie boards, bocce ball, corn h …see more

from $200 / night

$1300 / week

Book View

from $200 / night

24

Vacation apartment with shared pool in Isle of Palms

Coastal South Carolina / Isle of Palms

4 10 Min stay varies

  • 4 bedrooms
  • Sleeps 10
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
If you would like to catch the perfect wave next to the IOP Pier, enjoy a perfect day on the beach, or relax in comfort and style, you will find a perfect vacation at “Surfs Up”. Located at the beautiful complex, 1140 Ocean Blvd, Condominium #308 “Surfs Up” offers ocea …see more

from $546 / night

$1750 - $4314 / week

Book View

from $546 / night

24

Vacation apartment with shared pool in Isle of Palms

Coastal South Carolina / Isle of Palms

3 8 Min stay varies

  • 3 bedrooms
  • Sleeps 8
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
You’ll be sitting on top of the world during your next vacation at 407-A Shipwatch! This fabulous three bedroom, three bath condominium offers top of the world views from the fourth/fifth floor penthouse level at the popular Shipwatch Condominiums! Sporting the best p …see more

from $464 / night

$1353 - $3188 / week

Book View

from $464 / night

37

Isle of Palms Vacation condo rental

Coastal South Carolina / Isle of Palms

1 4 Min stay varies

  • 1 bedroom
  • Sleeps 4
  • Min stay varies
  • Beach/lakeside relaxation
  • Child friendly
  • Air conditioning
Oceanfront Condo/Beach Front Condo. Villa, 1 Bedroom + Convertible bed(s), 1 Bath, (Sleeps 4). Welcome to Sea Cabins, you came here to relax and enjoy the good life by the sea and our first floor end unit #132, just 7 steps will certainly help you accomplish thes …see more

from $153 / night

$730 - $944 / week

Book View

from $153 / night

(3) Excellent 

17

Condo rental in Isle of Palms with shared pool

Coastal South Carolina / Isle of Palms

1 4 3 nights min

  • 1 bedroom
  • Sleeps 4
  • 3 nights min
  • Beach/lakeside relaxation
  • Nearest beach 0.1 mi
  • Swimming pool
Enjoy an affordable getaway in this privately owned and maintained first floor condo, 1 block to the beach. Close to the action but far enough away to enjoy peace and quiet. ~~~~~ ** Rates include pet fees, cleaning or sales fees. Will add or deduct fees as appropria …see more

from $85 / night

$425 - $839 / week

Book View

from $85 / night

24

Vacation home rental

Coastal South Carolina / Isle of Palms

4 10 Min stay varies

  • 4 bedrooms
  • Sleeps 10
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
Enjoy step-outside-your door beach access and amazing oceanfront views, and you will discover why 10 Surf Lane is a home that truly exceeds any vacation’s dream. 10 Surf Lane is so unique on the Charleston Coast in that it is a four bedroom, three full bath private hom …see more

from $644 / night

$2241 - $6788 / week

Book View

from $644 / night

(4) Excellent 

20

Vacation villa with golf nearby in Isle of Palms

Coastal South Carolina / Isle of Palms

3 8 Min stay varies

  • 3 bedrooms
  • Sleeps 8
  • Min stay varies
  • Beach/lakeside relaxation
  • Nearest beach 1 mi
  • Child friendly
2 Bedrooms, plus a King Bed Sleeping Loft, 2.5 Bathrooms, Walk to Golf & Beach- Sleep 8 2 Links Clubhouse Villas is an adorable cottage in the private gated beach front resort community of Wild Dunes. The villa overlooks a beautiful tidal marsh and is only a shor …see more

from $195 / night

$1365 - $2450 / week

Book View

from $195 / night

(15) Excellent 

8

Vacation apartment in Isle of Palms

Coastal South Carolina / Isle of Palms

2 6 Min stay varies

  • 2 bedrooms
  • Sleeps 6
  • Min stay varies
  • Beach/lakeside relaxation
  • Swimming pool
  • Child friendly
This vacation rental is a 2 BR / 2 BA condo (3rd floor units) that is conveniently located across a quiet street from the ocean; near shopping, restaurants, & grocery store. My condo is very nicely decorated and expertly maintained. A fishing pier & onsite communi …see more

from $96 / night

$550 - $1127 / week

Book View

from $96 / night

24

Vacation apartment rental

Coastal South Carolina / Isle of Palms

2 4 Min stay varies

  • 2 bedrooms
  • Sleeps 4
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
“Live in the sunshine, swim the sea, drink the wild air…” while creating lifelong memories at Shipwatch 310B in Wild Dunes Resort. Emerson wrote these words years ago but must have been thinking about a place similar to 310B in Shipwatch. This gorgeous property is lo …see more

from $376 / night

$1050 - $2803 / week

Book View

from $376 / night

24

Isle of Palms Vacation home rental

Coastal South Carolina / Isle of Palms

4 12 Min stay varies

  • 4 bedrooms
  • Sleeps 12
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
The Island features a wide selection of vacation homes ranging from mansions that rent for $30,000 a week to the “JC Long” homes built following World War Two for returning veterans. Where Grand Pavilion 101 is not a classic WWII home, it is similar in that it is de …see more

from $532 / night

$1559 - $3850 / week

Book View

from $532 / night

(9) Very Good 

16

Apartment rental in Isle of Palms with shared pool

Coastal South Carolina / Isle of Palms

1 4 3 nights min

  • 1 bedroom
  • Sleeps 4
  • 3 nights min
  • Beach/lakeside relaxation
  • Swimming pool
  • Child friendly
Our little Slice of HEAVEN! CHARLESTON OFFERS THE BEST OF ALL WORLDS: INCREDIBLE BEACHES, YEAR ROUND FESTIVALS- ART & MUSIC, HISTORIC SIGHTSEEING, WORLD CLASS DINING, GREAT WEATHER, & MORE Many openings at great deals Dec - Feb, as low as $89 + tax per weeknights/non- …see more

from $129 / night

$890 - $1585 / week

Book View

from $129 / night

24

Vacation condo with shared pool, golf nearby in Isle of Palms

Coastal South Carolina / Isle of Palms

2 6 Min stay varies

  • 2 bedrooms
  • Sleeps 6
  • Min stay varies
  • Beach/lakeside relaxation
  • Nearest beach 0.1 mi
  • Swimming pool
Beautiful Wild Dunes villa overlooking pool. Spacious 1218 foot condo with dual master bedrooms each with 2 queen beds, ensuite bathrooms and balconies overlooking the pool. You will not find a cleaner, more beautifully appointed villa in Wild Dunes. Completely renovate …see more

from $150 / night

$1100 - $2050 / week

Book View

from $150 / night

(1) Excellent 

14

Vacation home with golf nearby in Isle of Palms

Coastal South Carolina / Isle of Palms

4 10 Min stay varies

  • 4 bedrooms
  • Sleeps 10
  • Min stay varies
  • Child friendly
  • Pet friendly
Welcome to our cute and casual raised beach home with our own private pool, at the gateway to Wild Dunes. Located inside the resort, our home is mere steps from the best WIDE UNSPOILED beach in Isle of Palms. Convenient to the Citadel Beach House, and on the bike path f …see more

from $299 / night

$2199 - $3695 / week

Book View

from $299 / night

30

Isle of Palms Vacation apartment rental

Coastal South Carolina / Isle of Palms

3 6 Min stay varies

  • 3 bedrooms
  • Sleeps 6
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
The recipe for the perfect vacation includes a wide beach, a warm breeze and the relaxing sound of the waves rolling into the shore. All of this and more can be found at 401 A Shipwatch in Wild Dunes Resort! This tropical delight boasts hardwood and ceramic tile floors …see more

from $456 / night

$1312 - $3279 / week

Book View

from $456 / night

(2) Excellent 

13

Vacation home rental

Coastal South Carolina / Isle of Palms

4 8 Min stay varies

  • 4 bedrooms
  • Sleeps 8
  • Min stay varies
  • Beach/lakeside relaxation
  • Child friendly
New this year, our property comes with a Wild Dunes Sportscard which allows our guests access to all the Wild Dunes resort amenities. Now you can enjoy the heated swim center pool, the grand pavilion pools overlooking the ocean, the new Palm Cove pool with zero-entry, t …see more

from $325 / night

$2600 - $3200 / week

Book View

from $325 / night

(1) Very Good 

10

Isle of Palms Vacation guest house rental

Coastal South Carolina / Isle of Palms

1 2 3 nights min

  • 1 bedroom
  • Sleeps 2
  • 3 nights min
  • Beach/lakeside relaxation
  • Swimming pool
  • Ask about children
SHIAWA-SEA COTTAGE is a 2 level Guest House located 2 blocks from the Atlantic Ocean, on Isle of Palms, SC, a residential beach community. Our moderate climate encourages Fall/Winter daytime, outdoor activities such as beach walking/running, biking and golfing. A gas …see more

from $175 / night

$1225 / week

Book View

from $175 / night

33

Vacation home rental

Coastal South Carolina / Isle of Palms

5 15 Min stay varies

  • 5 bedrooms
  • Sleeps 15
  • Min stay varies
  • Ask about children
  • Air conditioning
If you’re on the lookout for fun amenities and gorgeous top-of-the world Atlantic Views, let #12 on 54th Avenue be your starting point! This amazing 5 bedroom, 5 bath home was rebuilt nearly from scratch in 2015/2016. It truly is unique in design, almost as if it wer …see more

from $784 / night

$2784 - $7844 / week

Book View

from $784 / night

24

Vacation apartment with shared pool in Isle of Palms

Coastal South Carolina / Isle of Palms

2 6 Min stay varies

  • 2 bedrooms
  • Sleeps 6
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
It’s the reason we are called to the Island…Time Away at 12 A Mariner’s Walk! Make it memorable in this impressive, well-appointed condominium, located oceanfront with unbelievable views! Featuring two bedrooms (King, Queen, Sleeper Sofa), two full bathrooms, and a s …see more

from $391 / night

$1122 - $2754 / week

Book View

from $391 / night

(2) Very Good 

14

Cottage rental in Isle of Palms

Coastal South Carolina / Isle of Palms

2 6 Min stay varies

  • 2 bedrooms
  • Sleeps 6
  • Min stay varies
  • Child friendly
  • Air conditioning
Cute beach cottage fully furnished! Just 2 blocks from the beach and walking distance to front beach Isle of Palms shops and restaurants! Beautiful sun room, breakfast bar in the spacious kitchen, 2 bedrooms, 2 full bathrooms, laundry room with washer and dryer! Picket …see more

from $170 / night

$1100 / week

Book View

from $170 / night

24

Isle of Palms Vacation villa rental

Coastal South Carolina / Isle of Palms

3 6 Min stay varies

  • 3 bedrooms
  • Sleeps 6
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
2 Linkside Villa is a truly unique property in the Wild Dunes Resort that puts wildlife into the name Wild Dunes. This wonderful property offers truly amazing views of the tidal marsh, tidal forest, and views of Dewees Inlet, from its very own deck! All sort of wildli …see more

from $379 / night

$925 - $2181 / week

Book View

from $379 / night

(1) Excellent 

9

Vacation home with golf nearby in Isle of Palms

Coastal South Carolina / Isle of Palms

3 8 Min stay varies

  • 3 bedrooms
  • Sleeps 8
  • Min stay varies
  • Beach/lakeside relaxation
  • Nearest beach 0.4 mi
  • Child friendly
Built in 1955, this low-key, modest beach home is nestled under old oak trees in a quiet residential area just around the corner to the best beach on the East coast and its local shops. It's a quick walk to nearby restaurants and a grocery store, too. Charleston, one …see more

from $150 / night

$1000 - $1530 / week

Book View

from $150 / night

(1) Good 

24

Vacation home with swimming pool in Isle of Palms

Coastal South Carolina / Isle of Palms

5 10 Min stay varies

  • 5 bedrooms
  • Sleeps 10
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
Discover enchanting beach days and gorgeous ocean sunrises from the rooftop deck, while surrounded by luxurious amenities with a stay at 6 on 32nd Avenue. This newly constructed 3,400 square foot home has everything your family is searching for in a fantastic beach va …see more

from $1147 / night

$3005 - $7489 / week

Book View

from $1147 / night

24

Vacation apartment with shared pool in Isle of Palms

Coastal South Carolina / Isle of Palms

2 8 Min stay varies

  • 2 bedrooms
  • Sleeps 8
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
A relaxing and fun vacation is the name of the game at “Seas The Day”, 312 Seascape! Beginning with an expansive private deck, this beautiful two bedroom, two bath condominium has unbelievable oceanfront views! Located on the north-east side of the Island, “Seas The D …see more

from $412 / night

$1226 - $3043 / week

Book View

from $412 / night

24

Vacation apartment rental

Coastal South Carolina / Isle of Palms

1 5 Min stay varies

  • 1 bedroom
  • Sleeps 5
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
This wonderful condominium offers you the beach at your doorstep. “Sand Castle” is one of only a handful of properties on the Isle of Palms where you can walk off your screen porch and set your beach chair and umbrella on the beach. As beautiful as the ocean is at P …see more

from $347 / night

$1002 - $2395 / week

Book View

from $347 / night

24

Vacation apartment with shared pool in Isle of Palms

Coastal South Carolina / Isle of Palms

2 4 Min stay varies

  • 2 bedrooms
  • Sleeps 4
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
There is a lot to love at this beautiful two bedroom condominium located in the family friendly Shipwatch complex. Shipwatch at Wild Dunes Resort is a wonderful community, and features many outstanding amenities. “Beach Walker” is directly across from one of the most …see more

from $370 / night

$1017 - $2463 / week

Book View

from $370 / night

24

Apartment rental in Isle of Palms

Coastal South Carolina / Isle of Palms

2 4 Min stay varies

  • 2 bedrooms
  • Sleeps 4
  • Min stay varies
  • Ask about children
  • Air conditioning
If ocean views and a wonderful swimming pool are to the top of your vacation wish list, you can’t beat 201 H Tidewater! Located in the premier Wild Dunes Resort community, you’ll have a hard time deciding whether to stroll down to the ocean first, or spend a little t …see more

from $391 / night

$1123 - $2679 / week

Book View

from $391 / night

43

Isle of Palms Vacation home rental

Coastal South Carolina / Isle of Palms

7 12 Min stay varies

  • 7 bedrooms
  • Sleeps 12
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
Your mind will be wandering back to your perfect Isle of Palms vacation throughout the year after a week at this BRAND-NEW home, 4202 Palm Boulevard! Construction of this perfect island escape just completed (February, 2017)! Featuring seven bedrooms and seven full ba …see more

from $864 / night

$3184 - $9734 / week

Book View

from $864 / night

32

Home accommodation in Isle of Palms with swimming pool

Coastal South Carolina / Isle of Palms

6 14 Min stay varies

  • 6 bedrooms
  • Sleeps 14
  • Min stay varies
  • Nearest beach 0.1 mi
  • Swimming pool
  • Child friendly
I just love what a guest wrote me after a recent stay - she said that they booked Carolina Elegance as a mini family reunion having not been together in many years and her parents were getting older. They all arrived about the same time and as they entered the house …see more

from $545 / night

$3815 / week

Book View

from $545 / night

24

Vacation home in Isle of Palms

Coastal South Carolina / Isle of Palms

6 18 Min stay varies

  • 6 bedrooms
  • Sleeps 18
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
"A Taste of Charleston on the Isle of Palms" This extravagant brand new construction home on the Isle of Palms is luxurious in every way and has spared no expense for our guests. This 2009 new construction comes with a dual infinity pool and kiddy pool, over 200 sq ft …see more

from $1193 / night

$4113 - $10743 / week

Book View

from $1193 / night

24

Vacation apartment with shared pool in Isle of Palms

Coastal South Carolina / Isle of Palms

2 6 Min stay varies

  • 2 bedrooms
  • Sleeps 6
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
Ready for your well-deserved beach break? Come discover a wonderful island gataway at 321 D Shipwatch on the Isle of Palms. Located in the private Resort Community of Wild Dunes, this two bedroom and two bath condominium is perfect for two couples or a family looking …see more

from $370 / night

$1017 - $2507 / week

Book View

from $370 / night

27

Vacation cottage in Isle of Palms

Coastal South Carolina / Isle of Palms

3 6 Min stay varies

  • 3 bedrooms
  • Sleeps 6
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
If you have ever dreamed of having the perfect family vacation at the beach, you will find it at “Banana Pancakes”. During your search for the perfect family vacation you will start by driving to “Banana Pancakes” through a community founded in a portion of an old marin …see more

from $379 / night

$925 - $2088 / week

Book View

from $379 / night

24

Vacation home with swimming pool in Isle of Palms

Coastal South Carolina / Isle of Palms

7 12 Min stay varies

  • 7 bedrooms
  • Sleeps 12
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
Wake up to the serenity of the ocean and a day full of lavish amenities and fun diversions with a stay at the lavishly appointed “After Dune Delight”, 2400 Palm Boulevard. Currently under construction, this amazing home will feature 7,000 square feet of living space, 5 …see more

from $2071 / night

$6795 - $20599 / week

Book View

from $2071 / night

24

Isle of Palms Vacation home rental

Coastal South Carolina / Isle of Palms

6 14 Min stay varies

  • 6 bedrooms
  • Sleeps 14
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
It is said, “The sea lives in every one of us”. Where the sea might live within us every day, it is truly wonderful when we can live by it, even if only for a week! Your next vacation, 10 on 45th is the perfect place to make this a reality! Uniquely designed, 10 on 4 …see more

from $745 / night

$2454 - $6684 / week

Book View

from $745 / night

27

Isle of Palms Vacation apartment rental

Coastal South Carolina / Isle of Palms

1 5 Min stay varies

  • 1 bedroom
  • Sleeps 5
  • Min stay varies
  • Swimming pool
  • Ask about children
  • Air conditioning
For a relaxing vacation that’s filled with oceanfront views, refreshing breezes, and the sound of breaking waves, steer into 304 A Port O Call at Wild Dunes Resort! Offering a large screened porch and rooftop open deck, the views of the Atlantic and surrounding beaches …see more

from $340 / night

$967 - $2304 / week

Book View

from $340 / night

26

Isle of Palms Vacation home rental

Coastal South Carolina / Isle of Palms

5 12 Min stay varies

  • 5 bedrooms
  • Sleeps 12
  • Min stay varies
  • Ask about children
  • Air conditioning
South By South West, is the ideal heading to lead you to the perfect beach vacation on the Isle of Palms at 5 on 32nd Avenue. This beautiful home is modeled in a nautical theme, straight from a 1920’s racing sailing schooner. Heart of Pine floors, white wainscoting, …see more

from $697 / night

$2555 - $7039 / week

Book View

from $697 / night

1